A multidisciplinary community of researchers on a mission to improve human health.
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Broad Institute retweeted
We’re delighted to announce that the HCA Organizing Committee (OC) has selected Muzz Haniffa and Alexandra-Chloé Villani to be the next Co-Chairs of the HCA OC, and Shyam Prabhakar and Holger Heyn as co Vice-Chairs. #HumanCellAtlas @Muzz_Haniffa @villanilab @shyam_lab @hoheyn
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Survey of mitochondria proteomes across eukaryotes explores organelle’s role, suggests mitochondria originated late in eukaryotic evolution, and highlights possible drug targets for tropical diseases. broad.io/MitoCartaTreeOfLife
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New method allows scientists to connect disease-linked regulatory genetic variants to the genes they control. These variants are more likely to influence disease risk if they alter chromatin accessibility that then changes gene expression. broad.io/ImmuneCellAtlas
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Broad Institute retweeted
New work in @Nature with @dalygene led by @masakanai! We used population-scale chromatin and transcriptomic profiling of immune cells from FinnGen participants to connect disease-associated variants to gene regulation and disease risk.
nature.com/articles/s41586-0…
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The @novonordiskfond is renewing its commitment to Broad with a $53M investment. With Danish scientists, the Center will leverage massive-scale data, AI, and advanced cellular models to decode the genetic drivers of type 2 diabetes and obesity. broad.io/NNFCRenewal
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Broad, Boston Children's Hospital, and The Jackson Laboratory launched the Center for Therapeutic Genetics to build genetic medicines for rare disease as a repeatable practice, not a one-off breakthrough.
Hear from @davidrliu and @winstonxyan about what we're building and why.
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Broad Institute retweeted
Excited to share my first paper as a co-senior author, now published in Nature Genetics! @broadinstitute
Paper: nature.com/articles/s41588-0…
#NatureGenetics #AllofUs #PolygenicRiskScores #StatisticalGenetics
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Broad Institute retweeted
How does brain tissue become data? Through a massive collaborative effort supported by the Brain Initiative Cell Atlas Network (BICAN), learn how scientists are creating a comprehensive map of the human brain.
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Broad Institute retweeted
Brain tissue processing consistency is critical to quality data. Learn more about our collaborative effort, supported by the Brain Initiative Cell Atlas Network (BICAN), to develop the most comprehensive cellular map of the human brain ever.
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Broad Institute retweeted
Thrilled to share that Delphy is out yesterday in @Nature 🎉
Led by Patrick Varilly and built with Ben Fry and the @fathominfo team, Delphy brings scalable, near-real-time Bayesian phylogenetics to outbreak response, combining a radically faster inference engine with an intuitive, interactive interface.
Paper: nature.com/articles/s41586-0…
Try it: delphy.bio/
@sabetilab @broadinstitute @fathominfo @acegid_igh
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Broad Institute retweeted
@broadinstitute press release about Delphy, and the story of how our team first met 20 years ago at @MIT and reconnected during COVID ❤️
To aid in virus outbreak responses, Broad researchers and Fathom Information Design created Delphy.bio, a free web tool to reconstruct how a virus is spreading and changing using viral genomic data, reducing a months-long task to hours. broad.io/Delphy
ALT Artistic illustration of a phylogenetic tree that traces viral genetic mutations over time
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Broad Institute retweeted
✨ From Code to Cure, Building Foundation Models and AI Co-Scientists for Precision Genomic Medicines
💬 @lecong
🏫 Associate Professor, @StanfordMed; Co-founder, Phylo and Acelegen
📅 Thursday, Sept. 17 (tomorrow)
⏰ 4 - 5 p.m.
📍 Yellowstone at @broadinstitute (in-person only)
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Congratulations, @skoularidou!
Isaac Newton wrote in a letter "If I have seen further, it is by standing on the shoulders of giants"
My giants have been @d_spiegel, @ArnaudDoucet1, Petros Dellaportas, @caromitreka, @KonstDaskalakis and Christos Papadimitriou; I have been immensely privileged to learn from them
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To aid in virus outbreak responses, Broad researchers and Fathom Information Design created Delphy.bio, a free web tool to reconstruct how a virus is spreading and changing using viral genomic data, reducing a months-long task to hours. broad.io/Delphy
ALT Artistic illustration of a phylogenetic tree that traces viral genetic mutations over time
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Congratulations to @zhangf on being named a laureate of the 2026 Global Distinguished Engineer Award by the European Academy of Engineering! eae-academy.eu/news/2026-glo…
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Broad Institute retweeted
Get to know Karestan Koenen, PhD, Professor of Psychiatric Epidemiology, Department of Epidemiology, @HarvardHSPH & director the Population Mental Health Lab and Concentration. She also directs the Broad Trauma Initiative at @broadinstitute
➡️ Read Q&A: hsph.harvard.edu/epidemiolog…
ALT Koenen headshot with green graphic background.
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Broad Institute retweeted
Getting the right answer is not the same as understanding why. Beautiful work led by@AryaRao_ @eric_lander & a wonderful team, creating scientific sandboxes where we can expose gaps in AI reasoning, learn from failure & deliberately push the frontier. Come play in BroadBox🪣🏖️
Today, we introduce science sandboxes, a framework to measure the scientific capability of AI, and BroadBox, our @broadinstitute effort to build them across biology w/ @PardisSabeti @eric_lander + an amazing team 🧵
Preprint: arxiv.org/abs/2608.30165
Blog: aryarao.substack.com/p/measu…
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Broad Institute retweeted
Professor of Chemistry and Broad Institute Core Member Xiao Wang has been selected as the recipient of the 2027 Eli Lilly Award in recognition of her fundamental research in Biological Chemistry.
chemistry.mit.edu/chemistry-…
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New method from the @BlaineyLab lets scientists watch gene activity unfold in living cells over time, by engineering cells to package their own RNA into virus-like particles they release, ready for researchers to collect and sequence. broad.io/BlaineyLiveCell
ALT Diagram showing four irregular blue cells actively secreting small purple spheres outward, indicated by directional gray arrows.
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Broad Institute retweeted
We teamed up with @HLahdesmaki to develop and validate PepGen, the first fully generative model capable of synthesizing MHCII peptide binders conditioned on allele, partial sequences, and continuous affinity
Read the results here: academic.oup.com/bioinformat…
@broadinstitute
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