Cell Genomics@CellGenomics

Cell Genomics is a new gold #OpenAccess and #OpenScience research journal that represents the forefront of #genetics and #genomics 🧬

cell.com/cell-genomics/home
Joined June 2020
264 Photos and videos
Meet with us to discuss your research or to learn more about the publishing process! hubs.li/Q01msqBt0
1
2
17
Disease-associated loci share properties with response eQTLs under common environmental exposures dlvr.it/TVhmJ4

Disease-associated loci share properties with response eQTLs under common environmental exposures

Lin and Li et al. expose differentiating human stem cell cultures to nicotine, caffeine, or ethanol and identify genetic variants whose effects on gene expression emerge only after exposure. These...

cell.com
8
26
2,607
Single-cell multiomics across nine mammals reveals cell-type-specific regulatory conservation in the brain dlvr.it/TVgx1l

Single-cell multiomics across nine mammals reveals cell-type-specific regulatory conservation in...

Anderson et al. compare brain gene regulation across nine mammals, revealing that enhancer conservation extends beyond DNA sequence to include cell-type specificity and gene targets. Functional...

cell.com
17
79
6,139
Last chance to register and save! The early registration discount for #CPSsinglecellbiology2026 ends today. Join an exceptional speaker lineup in Munich for three days of science, networking & a little Christmas market magic. Register: hubs.li/Q04y16Kb0
292
MOSHPIT: Accessible, reproducible metagenome data science on the QIIME 2 framework dlvr.it/TVdF3n

MOSHPIT: Accessible, reproducible metagenome data science on the QIIME 2 framework

Ziemski et al. introduce MOSHPIT, a versatile software suite built on the QIIME 2 framework that simplifies complex shotgun metagenomic analysis. By integrating benchmarked tools into a unified,...

cell.com
380
Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved regions in humans dlvr.it/TVcP8h

Intraspecific sequence variation and complete genomes refine the identification of rapidly evolved...

Luo, Mangan, et al. identified 1,596 Consensus HAQERs, human genomic regions that rapidly evolved, from a 20-way alignment of T2T genomes containing both interspecific and intraspecific ape variati...

cell.com
4
11
1,332
Concentrating cell-type-specific transcriptional signatures in bone marrow from interspecies comparisons dlvr.it/TVZszW

Concentrating cell-type-specific transcriptional signatures in bone marrow from interspecies...

The authors present a framework to isolate condensed marker gene signatures by requiring both conserved cell-type specificity and conserved expression across multi-species scRNA-seq datasets. Bone...

cell.com
2
8
1,040
Pre-diagnosis plasma cell-free DNA reveals early signatures of prostate and breast cancer risk up to eight years prior to clinical detection dlvr.it/TVZhnv

Pre-diagnosis plasma cell-free DNA reveals early signatures of prostate and breast cancer risk up...

Cheng et al. profile genome-wide cfDNA methylation in archived, prospectively collected plasma sampled 2 weeks to 9 years before breast or prostate cancer diagnosis. Regulatory-element signatures...

cell.com
4
6
869
Science, networking, AND Munich’s Christmas markets! Join the international single-cell biology community in Munich, Dec 2–4, for #CPSsinglecellbiology2026. Register by Sept 25 to save: hubs.li/Q04xJNT00
1
1
2
324
Mutation timing, accumulation, and selection in the male germline shape inheritance risk for developmental disorders dlvr.it/TVW3B4

Mutation timing, accumulation, and selection in the male germline shape inheritance risk for...

Neville et al. combine trio whole-genome sequencing with ultra-accurate sperm sequencing to quantify how de novo mutation timing and selection shape transmittable disease risk. Early embryonic...

cell.com
1
4
518
Stressed-out immune cells dlvr.it/TVRNB5

Stressed-out immune cells

Connections between chronic stress, inflammation, and human diseases are well-established but poorly understood. In this issue of Cell Genomics, the effects of stress hormones on the immune system...

cell.com
336
Pouria Salehi Nowbandegani dlvr.it/TVRBc5

Pouria Salehi Nowbandegani

Dr. Laura Zahn asked Dr. Pouria Salehi Nowbandegani about their study, “Defining and cataloging variants in pangenome graphs,” and how they came to study this aspect of genomics.

cell.com
310
Jingjing Zhai and Edward S. Buckler dlvr.it/TVR550

Jingjing Zhai and Edward S. Buckler

Dr. Laura Zahn asked the authors, Dr. Jingjing Zhai and Dr. Edward (Ed) S. Buckler, to tell us about their research relating to their Cell Genomics paper, “PlantCAD2: A DNA foundation model for...

cell.com
1
338
Defining and cataloging variants in pangenome graphs dlvr.it/TVQckY

Defining and cataloging variants in pangenome graphs

Salehi Nowbandegani et al. introduce pantree, a framework for defining variants in pangenome graphs. By choosing a reference tree and cataloging non-tree edges, pantree resolves variants embedded in...

cell.com
1
5
29
2,736
Identifying independent causal cell types for human diseases and risk variants dlvr.it/TVQTlk

Identifying independent causal cell types for human diseases and risk variants

Kim et al. introduce CT-FM and CT-FM-SNP, probabilistic methods connecting GWAS associations with causal cellular contexts at genome-wide and SNP levels. Across 63 traits, they infer independent...

cell.com
6
47
4,173
Reporting and representation of population descriptors in public RNA-seq databases dlvr.it/TVQHrr

Reporting and representation of population descriptors in public RNA-seq databases

By combining repository metadata, genotype-inferred ancestry, and manual curation of publications, Gallego Romero et al. demonstrate that public RNA-seq datasets are dominated by samples from...

cell.com
4
725
Single-cell transcriptomics provides insights into the stress-immune interplay and informs disease risk dlvr.it/TVQB4c

Single-cell transcriptomics provides insights into the stress-immune interplay and informs disease...

Benavides et al. show that stress hormones affect immune cell types differentially, with a distinct cell type, CD163+ MonoMacs, displaying heightened stress-induced inflammation. Their findings...

cell.com
4
7
745
scXpand: Pan-cancer detection of T cell clonal expansion from single-cell RNA sequencing without paired single-cell TCR sequencing dlvr.it/TVPjhh

scXpand: Pan-cancer detection of T cell clonal expansion from single-cell RNA sequencing without...

Shorer et al. introduce scXpand, a machine-learning framework for pan-cancer detection of T cell clonal expansion from single-cell RNA sequencing, without paired TCR sequencing. Trained and tested...

cell.com
4
20
1,892
PlantCAD2: A DNA foundation model for interpreting genomes across flowering plants dlvr.it/TVPZPP

PlantCAD2: A DNA foundation model for interpreting genomes across flowering plants

Zhai et al. introduce PlantCAD2, a DNA foundation model pre-trained on 65 angiosperm genomes. Despite being 10-fold smaller, PlantCAD2 outperforms the 7-billion-parameter Evo2 on most plant-specific...

cell.com
1
2
391
Polygenic risk scores and plasma proteomics identify cancer-related proteins and trans-regulated protein networks dlvr.it/TVPNHW

Polygenic risk scores and plasma proteomics identify cancer-related proteins and trans-regulated...

Dutta et al. integrate cancer polygenic risk scores with plasma proteomics across 21 cancers to identify trans-regulated proteins associated with germline susceptibility variants using two compleme...

cell.com
313
Great science. New connections. Munich. Meet and network with leading researchers at #CPSsinglecellbiology2026, exploring single-cell biology, spatial technologies & AI. Early registration discount ends Sept 25: hubs.li/Q04wwfNG0
1
306
Load more