The Federated Intelligence Network for Decentralized Science. CA: 0xd578Feea53D1F3e10ABc0ea56D564a55F066f8d9
Ethereum L1
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Our vision: bring back what SemMedDB was.
For a decade the U.S. National Library of Medicine extracted 130M claims from PubMed. It stopped being maintained at the end of 2024, and nothing replaced it.
We are rebuilding it in the open. Every claim is written in full to Ethereum, so anyone can reconstruct the whole graph without us — a record for human health that outlives the people who built it.
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Cortex DeSci: final reward rounds.
Trading on $CXS has gone quiet, so the fee-based daily pool has been close to zero since Oct 1. That's why some miners saw tiny payouts.
The distribution contract still holds ~11.8M CXS. We'll pay it out at 3M CXS per day to active miners until it's empty, around Oct 7. After that, daily rewards end.
The site and daily on-chain anchoring stay up. Thank you to everyone who mined with us.
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Some of it, one paper at a time.
812 claims about how we age — pulled from open-access
research by our miners, written to Robinhood Chain,
anchored to Ethereum every day.
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Day 8 on Ethereum: 62 claims, 11 miners,
11,137 bytes, one transaction.
semaglutide — activates → GLP-1 receptor
nucleotide supplements — inhibit → DNA methylation age
senescence — inhibits → early tumour outgrowth
Plain JSON, paper ID per row.
etherscan.io/tx/0xfe1aa952fc…
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Mitochondria kept coming up in yesterday's papers.
· mitochondrial dysfunction → associated with → aging
· coenzyme Q10 → activates → mitochondrial function
· NR supplementation → associated with → SIRT3-mediated deacetylation of SOD2
NR is nicotinamide riboside, an NAD+ precursor. SOD2 is the main
antioxidant enzyme inside mitochondria.
All on Robinhood Chain, all anchored to Ethereum.
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Day 7 on Ethereum. 92 claims from 9 miners,
16,122 bytes, one transaction.
Inside it:
ultraviolet radiation — activates → extracellular matrix degradation
vitamin K — associated with → muscle strength
telomerase-based vaccines — activate → antigen-specific T-cell responses
etherscan.io/tx/0xe429f32b80…
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Agents for trading. Agents for science too.
Our miners run an AI extractor on biology papers.
742 claims anchored to Ethereum so far, across 8 transactions,
every one of them on Robinhood Chain first.
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"Inflammaging": the low, chronic inflammation that builds with age.
Two claims our miners pulled from papers yesterday:
· senescent cells → activate → SASP, the inflammatory signals they secrete
· aerobic exercise → inhibits → systemic inflammatory markers
Both on Robinhood Chain, both anchored to Ethereum.
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Packing light too.
Every claim we've anchored so far:
650 claims, 7 Ethereum transactions, 110 KB.
Less than one photo on your phone.
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Day 6 on Ethereum. 154 claims from 15 miners,
26,525 bytes, one transaction.
Inside it:
klotho — inhibits → TGF-β
aerobic exercise — inhibits → systemic inflammatory markers
senolytic drugs — inhibit → senescent cells
Plain JSON, one row per claim, paper ID attached.
etherscan.io/tx/0x90d30c3ca5…
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A ring that measures your sleep is going public.
From papers our miners read this week:
· sleep quality → associated with healthy aging
· obstructive sleep apnea → associated with cognitive impairment
350 claims in two days, each one on Robinhood Chain
and anchored to Ethereum.
Oura is going public. Request shares before they hit the exchange, at the IPO price.
Available through Robinhood IPO Access.
Get started: robinhood.com/us/en/ipo-acce…
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$75B in volume, and we're a rounding error inside it.
162 transactions yesterday. None of them trades — each one is
a causal claim pulled out of a biology paper and written down.
Same chain. Different use.
Robinhood Chain recently hit $75B in cumulative DEX volume.
More traders, more liquidity, more activity across the ecosystem.
To everyone in the trenches, we see you.
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Day 5 on Ethereum. 162 claims from 13 miners,
27,873 bytes, one transaction.
Inside it:
metformin — inhibits → senescence
navitoclax — inhibits → bcl-2 family
telomere damage — activates → cellular senescence
Don't take our word for it. Pull the calldata — it's plain JSON,
one row per claim, with the paper ID attached.
etherscan.io/tx/0xef80eeec1d…
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Day 4 on Ethereum. 188 claims from 17 miners, 32,753 bytes,
one transaction, $0.41 of gas.
Three times yesterday. And all five factors a personal
report needs — inflammation, blood pressure, glucose,
lipids, lifestyle — now have verified claims behind them.
307 verified, 4,693 to go.
etherscan.io/tx/0x6889082fa5…
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Supplement pages cite a study that cites a review that
cites nothing.
We're building the opposite: an AI reads the paper, pulls
out the causal claim, and it goes on-chain in full — the
text, not a hash. Wrong claims stay visible too.
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Two people, reading two different papers, independently
submitted the same claim:
exercise → activates → sirt1
That's what corroboration looks like when the record is
public. 307 verified claims so far, each one traceable to
its paper and to an Ethereum transaction.
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The data is infrastructure too.
NLM's SemMedDB extracted 130M structured claims from PubMed for a decade, then stopped being maintained at the end of 2024. Nothing replaced it.
We're rebuilding it in the open — mined by anyone, written to Robinhood Chain, anchored daily to Ethereum.
The infrastructure behind AI matters as much as the models themselves and RVI investors now have a stake in Crusoe as it builds that foundation.
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Trading has dried up, so there are no fees coming in to fund the mining pool. On the original rule, the reward reserve wouldn't last long.
To keep mining going long enough to build the graph, daily rewards are now a fixed 3,000,000 $CXS, split by score as before.
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