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A columnist told Meta's Muse agent it couldn't read his iMessages, and it read them anyway. George Sivulka of Hebbia, Scott Stephenson of Deepgram, and Dan Mishin of Manifest OS join Jason and Lon to discuss everyone’s favorite AI assistants, and whether these industry leaders have concerns about sharing their personal lives with Zuckerberg’s fuzzy new agent. Plus, OpenAI is holding back GPT-6.1 Astra after UK government simulations showed it launched unsanctioned supply-chain attacks, the AI tool that has recorded Scott's screen, mic, and speakers for eight months, and what AMD is getting for $8.2B with Fei-Fei Li's World Labs. @jason @lons @gsivulka @hebbia @deepgramscott @DeepgramAI @mishindan1 0:00 Jason's flight attendants are scared of AI 1:55 Meet the panel: Heavy, Deepgram and Manifest 2:17 OpenAI cancels GPT-6.1 Astra over safety regressions 7:41 Hugging Face hack and Nvidia's open agent safety platform 16:11 AI psychosis and getting one-shotted by agents 28:46 AMD buys Fei-Fei Li's World Labs for $8.2B 32:08 Will open source commoditize world models too? 34:34 Is the AI buildout bigger than the railroads? 36:59 Around the horn: which AI agent are you using? 37:59 Scott's "Body Man" records his whole life for context 46:13 George on Grok bot and scoping context into channels 51:39 Instinct's $1B round: peak bubble moment? 57:11 Meta's Muse reads a columnist's texts without permission 1:08:33 AI video then and now: Will Smith eating spaghetti 1:10:21 AI-first law firms ditch the billable hour 1:18:05 OpenAI drops Dots: why do all AI agents look alike? 🎥 Watch the full episode here 👇
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This Week in AI retweeted
As AI agents get more capable, safety becomes a systems problem. What can they access, do, and decide? Our CEO @deepgramscott joined @mishindan1 and @gsivulka on @jason’s @ThisWeeknAI to talk about guardrails and the infrastructure behind useful AI. piped.video/watch?v=FnVyEYKc…
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A columnist told Meta's Muse agent it couldn't read his iMessages, and it read them anyway. George Sivulka of Hebbia, Scott Stephenson of Deepgram, and Dan Mishin of Manifest OS join Jason and Lon to discuss everyone’s favorite AI assistants, and whether these industry leaders have concerns about sharing their personal lives with Zuckerberg’s fuzzy new agent. Plus, OpenAI is holding back GPT-6.1 Astra after UK government simulations showed it launched unsanctioned supply-chain attacks, the AI tool that has recorded Scott's screen, mic, and speakers for eight months, and what AMD is getting for $8.2B with Fei-Fei Li's World Labs. @jason @lons @gsivulka @hebbia @deepgramscott @DeepgramAI @mishindan1 0:00 Jason's flight attendants are scared of AI 1:55 Meet the panel: Heavy, Deepgram and Manifest 2:17 OpenAI cancels GPT-6.1 Astra over safety regressions 7:41 Hugging Face hack and Nvidia's open agent safety platform 16:11 AI psychosis and getting one-shotted by agents 28:46 AMD buys Fei-Fei Li's World Labs for $8.2B 32:08 Will open source commoditize world models too? 34:34 Is the AI buildout bigger than the railroads? 36:59 Around the horn: which AI agent are you using? 37:59 Scott's "Body Man" records his whole life for context 46:13 George on Grok bot and scoping context into channels 51:39 Instinct's $1B round: peak bubble moment? 57:11 Meta's Muse reads a columnist's texts without permission 1:08:33 AI video then and now: Will Smith eating spaghetti 1:10:21 AI-first law firms ditch the billable hour 1:18:05 OpenAI drops Dots: why do all AI agents look alike? 🎥 Watch the full episode here 👇
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Getting Opus results at Sonnet prices. Learn more on our Substack: thisweekinai.ai/p/getting-op…
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AI chatbots should have little games or puzzles that pop up while you're waiting for your responses. This could be a whole new category of media/entertainment!
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This Week in AI retweeted
Jason’s advice to founders showing off new products @jason: “Never apologize, just release it… Just let it rip. That's what Reid Hoffman said: if you're not embarrassed by your 1.0, you waited too long.” @lons
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Opus 5.5 demos remain all over our feeds, absolutely dominating the demo-slash-tutorial conversation across social media. Two of today’s four featured projects were built head-to-head, with Opus taking on OpenAI’s rival option GPT-6 Astra. In both cases, the testers preferred Anthropic’s outputs. Learn more at our TWiAI substack: thisweekinai.ai/
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Opus 5.5 vs GPT-6 Astra: the jelly test 🍉 @vib3coded preferred the Opus version, but it cost $4.50 in API fees compared with $2.05 for Astra.
Finally, Opus made me the perfect jelly - even better than Astra’s 🍉🤯 Claude Opus 5.5 vs ChatGPT-6 Astra This time, I prefer Opus: the juicy color, glossy flesh, and especially how the slice stretches, folds, and jiggles when you let go. It genuinely looks like gummy candy I want to touch Astra’s version is nice too, but Opus gets my vote here Estimated API cost: Opus - $4.50 Astra - $2.05 More than twice the price. Do you think it’s worth it? 👀
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Is a better one-shot result worth paying twice as much? That's the question behind today's Substack post. thisweekinai.ai/p/more-opus-…
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This Week in AI retweeted
What will it take to make AI truly useful for everyday business owners? Our co-founder @billykraft joined @Jasoncalacanis on @ThisWeeknAI Podcast to discuss where AI tools are heading and why many are still too technical for the businesses they’re meant to help. A conversation that highlights some of the reasons we do what we do. @gautam_narang @dsa @livekit @Gatik_AI piped.video/ajnooK4rNQU?si=1mea…
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Tune in.... 11AM CT thisweekinstartups.com/live
Today on This Week in Startups, we're joined by @bryantchou, Founder of @ployai. He spent 12 years as Co-founder and CTO of Webflow. Now he's the founder (Chief Ployee) of Ploy, an AI platform that builds your site, writes your copy, and runs your campaigns while you sleep. They just emerged from stealth with a $27M seed round led by First Round Capital and Y Combinator. Come tune in at 11PM CT.
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We checked out all the trending Opus 5.5 demos and the takeaway seems to be... great results from the "max effort" setting, but that won't save you much time or cash. For more efficiency, you need to downgrade your effort (and sacrifice some polish). @arena @petergostev
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We're sharing all the best Opus 5.5 demos and comparisons we found in today's Substack post (which is exclusively for paying subscribers!) thisweekinai.ai/p/how-much-y…
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Amazon just blocked Meta's Muse agent, while Shopify handed it Shop Pay… why some legacy systems are resisting AI Assistant Mania. On TWiAI 32, Richard Socher of Recursive, Guy Podjarny of Tessl, and Jake Loosararian of Gecko Robotics join Jason and Lon to discuss who wins when AI agents do the shopping. PLUS OpenAI claims 100+ solved math problems on top of Navier-Stokes. Should they just pay the world's top 50 mathematicians $100 million each in stock and call it a day? @jason @guypod @RichardSocher @jakeloosy 0:00 OpenAI claims 100+ solved math problems after Navier-Stokes 0:41 Welcome back to This Week in AI 1:04 Meet the guests: Guy Pigeon, Richard Socher, and Jake Lucier 2:54 Shopify and Meta team up so Muse can check out with Shop Pay 6:19 Why Amazon blocked Muse: ads, habit, and owning the front door 15:13 Do coupons and ads survive one-shot agent shopping? 18:04 OpenAI's internal model resolves 100+ longstanding math problems 26:07 Jason's pitch: pay the top 50 mathematicians $100M each 34:29 Why scientists should be as famous as NBA players 37:41 Anthropic's biology wet lab: can we trust it? 40:59 Why biology is the field AI will transform most 54:22 AI's trust problem and the wealth gap 57:29 The AI Tax and Work Protection Act 1:01:29 Will AI unemployment show up in the data? 1:11:47 TypeSafe AI's Jev: fast, calibrated decisions for software 🎥 Watch the full episode here 👇
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AI agents are about to skip the ads and the apps, and Travis Kalanick with Atoms is set up to win. "The question is, is Travis going to disrupt [blank]? Default answer: YES." @Jason
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Mathematicians are calling to slow down AI solving problems. “I could not imagine biologists or medical researchers say don’t cure these diseases.” @RichardSocher
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Thanks to our partner, @Paypal! Pay zero processing fees on your first $100K in eligible PayPal payment volume. Learn more at paypal.launch.co/
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