All the minds in the world. Now one question away. We’ve raised $16M from @sequoia to build @withdelphi - create your digital mind & turn your expertise into living, interactive conversations that scale globally. See how our customers use it below 👇🏼

🚨Very Exciting Announcement!🚨 We’re officially releasing My Digital Mind at StayCurious Metabolism Substack. 🔗staycuriousmetabolism.substa… But let me give you a little context. Over the past year, StayCurious Metabolism has grown from its infancy to become a top bestseller on Substack and, by far, the most often #1 Top Rising Science newsletter on the platform. In fact, we’ve spent more time at #1 on the Rising Science leaderboard in 2026 than all other science newsletters combined. 🫵 And that’s all thanks to you, your enthusiasm, and your curiosity. But as we’ve scaled, one of the challenges I’ve faced as a creator is the limitation of my own time. As much as I’d love to respond to every comment, answer every question, and correspond with each of you personally, there simply aren’t enough hours in the day. So, we’ve been working on something special. We’ve partnered with Delphi @withdelphi to create a digital version of my mind, trained on my entire body of work. That includes >300 letters, >500 videos, dozes of papers, posts, and thousands of hours of podcast content. In fact, it's trained on >4.5 million words of my original work, which is more than All the Harry Potter Books and all the Lord of the Rings Trilogy combined times three! And it's growing every day! This isn’t just a random chatbot. It’s a digital facsimile of my brain, built around my scientific interests, research, explanations, and perspectives, that you can interact with at your leisure. Want to explore a topic from one of my letters? Ask a follow-up question about a video? Dig deeper into the science of metabolism, nutrition, or longevity? Now you can. And unlike me, my digital mind doesn’t need to sleep! 📢 Built With You, for You We first launched this tool to our founding members about a month ago, giving them early access to help us beta-test the experience. The feedback has been phenomenal. “I used Delphi like I would Claude and ChatGPT. I thought Delphi had better depth in terms of mechanism of action. It really helped me understand a nagging shoulder injury that I have. I like the idea that the outputs are tied to Nick’s knowledge base. Feels more nuanced.” “I get trustworthy information and perspectives highly relevant to my health and well being that I can’t get anywhere else.” “The interaction during the commentary was what I would expect from a knowledgeable and caring clinician.” And this is just the beginning. As my body of work grows, so will the knowledge and functionality of this tool. And the more you use it, the more feedback we’ll have to continue refining and improving the experience. My hope is that it becomes an increasingly useful resource for exploring the science, revisiting ideas, and satisfying your curiosity whenever inspiration strikes. 🫂 The Human Touch Isn’t Going Anywhere Let me emphasize one thing: StayCurious Metabolism will never lose its human touch. I’ll still be here, writing letters, engaging in the comments, and sharing the science that excites me. But as our community continues to grow, I want to find new ways to make this experience more personal, not less. And that’s what my digital mind is all about. It’s a way to give you greater access to my body of work, help you explore the questions that matter to you, and make our growing library of scientific content more interactive and accessible. 🙌 Give It a Whirl! Premium members (net cost less than 67 cents per 3,000 word deep dive) get unlimited access. Free subscribers get a free trial. I look forward to continuing to learn, explore, and grow together. #StayCurious

Imagine two people using AI every day for ten years. One becomes much better at thinking. The other can barely think without it. I’m already seeing hints of the second outcome: people producing results they can’t explain or defend. It feels like the beginning of Idiocracy. I asked @jimkwik how to avoid becoming that second person. He’s one of the leading experts in memory and accelerated learning, and has spent three decades coaching CEOs, elite athletes, Hollywood actors, and TED speakers on how to use their minds better. Jim shared the process he uses to keep himself thinking while using AI. It’s called BUILD: B - Brainstorm what you already know. U - Understand the real problem. I - Imagine three possible solutions. L - Leverage AI to expose your blind spots. D - Decide what to do. AI comes fourth. It has your thinking to challenge, and you still have to make the call. On this week’s episode of The Library of Minds, I spoke with Limitless Daily author Jim Kwik about why learning still matters when answers are instant. 0:48 - What Exceptional Minds Do Differently 3:03 - Digital Dementia Is Real 11:05 - CrossFit for Your Mind 21:13 - Raising Kids Who Do Hard Things 33:23 - The Illusion of Learning 43:26 - The Coming Meaning Crisis 52:01 - Do This Before Asking AI 57:24 - You Can't Outperform Your Self-Image 75:38 - Ask Jim Anything, Anytime Chat with his Delphi: delphi.ai/jimkwik

One of the strangest parts of becoming a founder is realizing your team can’t tell which of your ideas are ideas - and which are instructions. You think you’re thinking out loud. They think the strategy changed again. @AlisaCohn, named the world’s #1 startup coach by Thinkers50, put it simply: founders generate ideas, teams hear priorities. At some point, protecting the team means keeping some ideas to yourself, and being painfully clear when one actually becomes the priority. New episode of The Library of Minds with Alisa Cohn. Join the conversation with her Delphi: delphi.ai/alisacohn 1:09 - Founder Mode: What Everyone Gets Wrong 4:58 - High Standards Without Micromanaging 8:13 - Death by Being Polite 14:15 - Why You Can't Copy Elon Musk 20:48 - Founders, Please Keep Your Ideas to Yourself 22:48 - The #1 Hiring Mistake with AI 35:11 - Dealing with Imposter Syndrome

Great piece from @Bloomberg on how therapists are using Delphi - not to replace sessions, but to help people explore their worldview & values before committing Finding the right therapist is deeply personal. Now you can get a feel for someone before ever getting on a call

Julie Zhuo spent 14 years at Facebook and eventually ran design for the Facebook app. Then she started her own company and realized she couldn't copy Facebook. Her explanation was pretty simple: “I’m not Mark.” @joulee thinks companies have personalities just like people do. Their strengths and weaknesses often come from the same traits, which means copying another great company’s operating system can actually make you worse. I think about this a lot. We spend so much time studying how Stripe hires, how Airbnb designs, how Meta ships, how Jobs presented... The useful question probably isn't “what do the best companies do?” It's “what are we unusually good at, and what kind of company should exist around that?” Really loved this conversation with Julie on The Library of Minds 0:58 - Why She Refused the CEO Title 6:48 - Delete Every Meeting but One 12:19 - The Oldest Interface Always Wins 15:40 - From Intern #1 to Facebook's Design Leader 21:08 - Writing the New Manager Bible 24:45 - How to Manage Agents

.@travisk on the little details that helped Uber beat Lyft: “I needed to subsidize rides to gain market share. When I gain market share there's a network effect because if I'm bigger, then my system is more efficient and if I'm more efficient than them, they have to subsidize more than I do to compete with me. This is why Lyft is smaller than Uber because we were better at this and people don't really know that's what it takes. But how do you get efficiency edge? Efficiency edge starts when somebody even downloads the app and signs up. If it's easier to sign up on one versus another you have an efficiency edge. If it's easier to call a vehicle and get it to you without problems, you have an efficiency edge because you'll have less support. If the cars are moving to where the demand is because the driver app has good ways to point drivers to the right place that means you have shorter pickup time, that’s another efficiency edge. And efficiency edge means you get bigger faster.”

Granola now connects directly with @withdelphi. So your notes can flow directly to your digital mind. And your team, customers and job candidates can ask anything and get the answer.