futurist rand.longevity@gmail.com
Massachusetts, USA
- Tweets 86,481
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would you get a brain chip implant when it gives you an advantage over the rest of the population?
its already happening, consumer is a few years away so start thinking about it
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today was a big day for biology
AI just found a new process in the human body, we are pushing the frontier
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Insilico Medicine @InSilicoMeds wants to use AI to cure aging
they are calling the research program "Longevity Vaccines."
here's how it would work:
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google just used AI to predict the effects of 9 billion possible changes to human DNA
the future is awesome
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AI helped pick the target and design the drug, now Rentosertib has human data showing 6 aging clocks pointing younger
its really exciting what is happening in science right now
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your DNA does matter for aging, but way less than you think
a good diet and excerise beats DNA every time
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what if medicine could rejuvenate your body faster than you age?
thats the idea behind Longevity Escape Velocity
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astra scores 98.6% on ARC-AGI-3
it looks like we share the planet with another general intelligence now
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this is wild, aging tests are hiding in plain sight
a CT scan of the chest reveals the age of major organs
- lungs
- heart
- aorta
- coronary artery
- pulmonary artery
ai was trained to read the CT and score each organ its own age, then ran it on 35,000 simulations
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all you have to do is Stay Alive! great work here from @drallibrown
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senescent cells own damaged DNA leaks into the cytoplasm, so the cell pumps out inflammatory signals forever, that same dna damage prevents it own recycle system
just floats around your body spreading damage and they keep adding up the longer you live
clear them out of old individuals and lifespan extends, this is what senolytics are for
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- senolytics
- epigenetic reprogramming
- stem cell therapy
- lab grown organs
- brain-computer interface
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oh damn happy skynet day, a glimpse into our future!
dont worry our system will be much safer
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the science behind why working out is so good for you:
PGC-1α - driving mitochondrial biogenesis and increasing your ATP
ACTN3 - shape strength, power, and endurance potential
BDNF - brain plasticity, learning, memory, and long-term neural health
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this is how we went from yamanaka factors to safe epigentic reprogramming
sometimes it really does come down to one gene, biology is wild
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researchers treated old mice with opaganib, a drug that blocks an enzyme called SphK2
the treatment helped aging blood stem cells work better, improved immune function, and helped the mice live longer.
also showed promising effects in aged human cells in the lab
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its brutal but another 150,000 people are going to die today
the sooner we cure aging, the more people get to live
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yep I was just talking about this the other day, AI is clearly going to cure cancer, not even a debate now
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as brain cells age, they lose the epigenetic control that keep the right genes on, that new DNA expression → inflammation
good to see another paper confirm what we already know, epigentic drift is a major driver of aging
if we can restore that youthful epigenetic control (currently testing in the human eye), we can reverse parts of the aging phenotype rather than just slow it down, a complete reversal.
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would you have a child with a humanoid robot if the child could be biologically human? you could pick all the genes the child would inherit, just like this
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this is a very strong signal (150,000+ subjects) that exercise delays aging, been waiting on this study for a while.. results are legitimate
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just thinking about a crime, could become a crime
🚨ChatGPT reported man to the FBI
A 25 year old Goldman Sachs employee was using ChatGPT to vent about his girlfriend and shared some violent fantasies. ChatGPT flagged the conversation and it was forwarded to the FBI. They used the conversation to get a search warrant and charge him with aggravated stalking, written threats to kill, and unlawful use of a cellphone. He plead guilty and got 8 years probation for the chat.
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