Research lab of Dr. Stephen Waggoner. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer. @labwaggoner.bsky.social
Cincinnati, OH
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Waggoner Lab retweeted
INSANE...NK therapy for Alzheimer's seems to work in people...
globenewswire.com/news-relea…
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Multiomic analyses identify RORC-expressing DCs enriched in patient-derived malignant ascites and enable functional evaluation @SciImmunology
science.org/doi/10.1126/scii… @villanilab @MGHMedicine
@KlempnerSam
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Lung anthelmintic responses during hookworm infection are regulated by skin-derived γδ T cells
science.org/doi/10.1126/scii… @SciImmunology @PH_Papotto @ProfJudiAllen
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A novel KIR2DS4:HLA-B*35 interaction axis that predicts patient survival, in both haplo-identical and fully matched, HCT @BloodPortfolio @PeterChockley @OhioState
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Review @J_Immunol
Context-dependent regulation of cytotoxic T lymphocytes by nuclear receptors
academic.oup.com/jimmunol/ar…
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Waggoner Lab retweeted
皮膚の再生を担う表皮前駆細胞で、がん抑制遺伝子p53の欠失によりWntシグナルの空間的勾配が形成され、この配置が変異細胞クローンの拡大と正常組織への進展を促すことを示した論文がScience誌に発表されました。
science.org/doi/10.1126/scie…
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Waggoner Lab retweeted
Autoantibody landscapes in Long COVID with neurological symptoms show heterogeneity without a shared disease signature
Congrats to @debanjana_c, Michael Wilson, Sam Pleasure and colleagues!
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Helios directly controls Tcf1, Lef1, Id3, and Bach2 to regulate effector Treg generation and terminal differentiation @JExpMed
rupress.org/jem/article/223/…
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GABPA ais critical regulator of STING expression, where Targeting GABPA suppresses pathogenic IFN responses in lupus patients @JExpMed
rupress.org/jem/article-abst…
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All in the family: a population-scale perspective on genetic networks of autoimmune disease @jclinicalinvest
jci.org/articles/view/211202
jci.org/articles/view/205952
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Small populations, big impact: leveraging rare disease gene therapies to benefit millions @jclinicalinvest
jci.org/articles/view/212036
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Functional evaluation of TCR-pMHC pairs at scale allows in silico TCR reactivity prediction @ImmunityCP
cell.com/immunity/fulltext/S… @Schumacher_lab @NKI_nl
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Distant lymph nodes compensate for resected tumor-draining lymph nodes during cancer immunotherapy @ImmunityCP @harvardmed
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Nutrient deprivation promotes Th9 cell senescence to compromise persistence, highlighting the potential of targeting ZAK to rejuvenate CAR-Th9 cells for solid tumor therapy @ImmunityCP
cell.com/immunity/fulltext/S…🇨🇳
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An orphan protein integrates circadian, dietary, and environmental signals to control brown fat metabolism
science.org/doi/10.1126/scie…
science.org/doi/10.1126/scie…
@ScienceMagazine @IuliiaKaravaeva @Z_GerhartHines 🇩🇰
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Women make up more than half the population, but most of what we know about women’s biology comes from extrapolation of studies in men @ScienceMagazine
science.org/doi/10.1126/scie…
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Review: Reframing menopause and menopause hormone therapy as opportunities for healthy aging
science.org/doi/10.1126/scie… @LiisaGalea
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Review: Sex-specific mechanisms of chronic pain
science.org/doi/10.1126/scie… @hollyingrahamSF
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