Research lab of Dr. Stephen Waggoner. Opinions expressed are Dr. Waggoner's alone and not on behalf of lab staff or employer. @labwaggoner.bsky.social

Cincinnati, OH
Based in United States
@biorxivpreprint @CincyResearch GM-CSF Programs Alveolar Macrophages to Maintain Pulmonary Lymphocyte Homeostasis biorxiv.org/content/10.64898…
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Multiomic analyses identify RORC-expressing DCs enriched in patient-derived malignant ascites and enable functional evaluation @SciImmunology science.org/doi/10.1126/scii… @villanilab @MGHMedicine @KlempnerSam
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Lung anthelmintic responses during hookworm infection are regulated by skin-derived γδ T cells science.org/doi/10.1126/scii… @SciImmunology @PH_Papotto @ProfJudiAllen
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Review @J_Immunol Context-dependent regulation of cytotoxic T lymphocytes by nuclear receptors academic.oup.com/jimmunol/ar…
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皮膚の再生を担う表皮前駆細胞で、がん抑制遺伝子p53の欠失によりWntシグナルの空間的勾配が形成され、この配置が変異細胞クローンの拡大と正常組織への進展を促すことを示した論文がScience誌に発表されました。 science.org/doi/10.1126/scie…
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Waggoner Lab retweeted
Autoantibody landscapes in Long COVID with neurological symptoms show heterogeneity without a shared disease signature Congrats to @debanjana_c, Michael Wilson, Sam Pleasure and colleagues! insight.jci.org/articles/vie…
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@biorxivpreprint A pro-inflammatory effector-memory T cell program links peripheral EBV priming to CNS autoimmunity biorxiv.org/content/10.64898…
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Helios directly controls Tcf1, Lef1, Id3, and Bach2 to regulate effector Treg generation and terminal differentiation @JExpMed rupress.org/jem/article/223/…
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GABPA ais critical regulator of STING expression, where Targeting GABPA suppresses pathogenic IFN responses in lupus patients @JExpMed rupress.org/jem/article-abst…
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All in the family: a population-scale perspective on genetic networks of autoimmune disease @jclinicalinvest jci.org/articles/view/211202 jci.org/articles/view/205952
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Small populations, big impact: leveraging rare disease gene therapies to benefit millions @jclinicalinvest jci.org/articles/view/212036
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Functional evaluation of TCR-pMHC pairs at scale allows in silico TCR reactivity prediction @ImmunityCP cell.com/immunity/fulltext/S… @Schumacher_lab @NKI_nl
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Distant lymph nodes compensate for resected tumor-draining lymph nodes during cancer immunotherapy @ImmunityCP @harvardmed cell.com/immunity/fulltext/S…
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Nutrient deprivation promotes Th9 cell senescence to compromise persistence, highlighting the potential of targeting ZAK to rejuvenate CAR-Th9 cells for solid tumor therapy @ImmunityCP cell.com/immunity/fulltext/S…🇨🇳
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An orphan protein integrates circadian, dietary, and environmental signals to control brown fat metabolism science.org/doi/10.1126/scie… science.org/doi/10.1126/scie… @ScienceMagazine @IuliiaKaravaeva @Z_GerhartHines 🇩🇰
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Women make up more than half the population, but most of what we know about women’s biology comes from extrapolation of studies in men @ScienceMagazine science.org/doi/10.1126/scie…
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Review: Reframing menopause and menopause hormone therapy as opportunities for healthy aging science.org/doi/10.1126/scie… @LiisaGalea
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Review: Sex-specific mechanisms of chronic pain science.org/doi/10.1126/scie… @hollyingrahamSF
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